• Erida Manalu Fakultas Kedokteran Universitas Kristen Indonesia Jakarta
Keywords: nephrotic syndrome, steroid resistant nephrotic syndrome (SNRS), remission, proteinuria


Steroid Resistant Nephrotic Syndrome (SNRS) is a Nephrotic Syndrome that fails to achieve remission after full and alternative doses of corticosteroids. Determination of remission is done by monitoring levels of protein in the urine. The presence of persistent proteinuria in three examinations for one week showed that the patient failed to achieve remission. A boy, 2 years old with symptoms of anarchic edema, massive proteinuria, hypoalbuminemia, and hyperlipidemia suitable for Nephrotic Syndrome. Patients have received full-dose and alternative prednisone therapy. The urinalysis results showed that the patient had persistent proteinuria and thus was diagnosed as a Steroid-Resistant Nephrotic Syndrome. The purpose of this paper is to increase knowledge about Nephrotic Syndrome and to prevent the occurrence of Steroid-Resistant Nephrotic Syndrome (SNRS) and subsequent complications. The method used is library research with an explorative descriptive approach with case studies and literature that are objective, analytical, and systematic. It can be concluded that proteinuria examination is important to find out the occurrence of remission in SN patients is also important to determine the success of SNRS therapy and predict progression to terminal renal failure.