• Arvianto Rumah Sakit Kepresidenan RSPAD Gatot Soebroto
  • Ezra Oktaliansah Departemen Anestesiologi dan Terapi Intensif RS dr.Hasan Sadikin/ Fakultas Kedokteran Universitas Padjajaran
  • Suwarman Departemen Anestesiologi dan Terapi Intensif RS dr.Hasan Sadikin/ Fakultas Kedokteran Universitas Padjajaran


sepsis, intra-abdominal infection, fluid therapy


Intra-abdominal infection is the second most common cause of sepsis and death due to infection in patients admitted in the Intensive Care Unit (ICU). The cornerstones of effective treatment of intra-abdominal infection are early recognition, adequate source control, and appropriate antibibiotic therapy. Adequate resuscitation with early vasopressor is very important. Empirical antibiotics administration for sepsis and sepstic shock due to complicated intra-abdominal infections can follow the guidelines of The Infection Diseases Society of America (IDSA) or antibiotic guidelines in Indonesia. Postoperative care in ICU must be carried out optimally, including by providing mechanical ventilation support and appropriate fluid therapy. This case report will describe management of sepsis caused by diffuse perforation due to duodenum perforation at ICU RSPAD Gatot Soebroto in August 2020. In this paper, we use the case report method with a retrospective approach and descriptive analysis. In this case, the patient was on admission with mechanical ventilation and moved to ward after 3 days being admitted to ICU. The conclusion of this paper is sepsis mortality rate due to diffuse perforation is still high, it can be caused by its complication and the need to treat in ICU for long term period.


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